The capsular polysaccharide of Enterococcus faecalis and its relationship to other polysaccharides in the cell wall.
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ABSTRACT:
SUBMITTER: Hancock LE
PROVIDER: S-EPMC122232 | biostudies-literature | 2002 Feb
REPOSITORIES: biostudies-literature
Publications
The capsular polysaccharide of Enterococcus faecalis and its relationship to other polysaccharides in the cell wall.
Hancock Lynn E LE Gilmore Michael S MS
Proceedings of the National Academy of Sciences of the United States of America 20020201 3
With the goal of identifying and characterizing traits of Enterococcus faecalis that play key roles in human disease, we identified an operon specifying synthesis of a capsular carbohydrate of the type most commonly expressed by clinical isolates. This surface-exposed carbohydrate consists of glycerol phosphate, glucose, and galactose residues, and its biosynthesis is encoded by a determinant that includes 11 ORFs. Insertional inactivation of genes in this pathway yielded mutants with enhanced s ...[more]
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2021-11-03 | PXD023265 | Pride