Ontology highlight
ABSTRACT:
SUBMITTER: Posthuma D
PROVIDER: S-EPMC1224534 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Posthuma Danielle D Luciano Michelle M Geus Eco J C de EJ Wright Margie J MJ Slagboom P Eline PE Montgomery Grant W GW Boomsma Dorret I DI Martin Nicholas G NG
American journal of human genetics 20050701 2
Between 40% and 80% of the variation in human intelligence (IQ) is attributable to genetic factors. Except for many rare mutations resulting in severe cognitive dysfunction, attempts to identify these factors have not been successful. We report a genomewide linkage scan involving 634 sibling pairs designed to identify chromosomal regions that explain variation in IQ. Model-free multipoint linkage analysis revealed evidence of a significant quantitative-trait locus for performance IQ at 2q24.1-31 ...[more]