Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials.
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ABSTRACT:
SUBMITTER: Hartgerink JD
PROVIDER: S-EPMC122734 | biostudies-literature | 2002 Apr
REPOSITORIES: biostudies-literature
Publications
Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials.
Hartgerink Jeffrey D JD Beniash Elia E Stupp Samuel I SI
Proceedings of the National Academy of Sciences of the United States of America 20020402 8
Twelve derivatives of peptide-amphiphile molecules, designed to self-assemble into nanofibers, are described. The scope of amino acid selection and alkyl tail modification in the peptide-amphiphile molecules are investigated, yielding nanofibers varying in morphology, surface chemistry, and potential bioactivity. The results demonstrate the chemically versatile nature of this supramolecular system and its high potential for manufacturing nanomaterials. In addition, three different modes of self- ...[more]
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