Dataset Information
Highways of gene sharing in prokaryotes.
Ontology highlight
ABSTRACT:
SUBMITTER: Beiko RG
PROVIDER: S-EPMC1242295 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
Publications
Highways of gene sharing in prokaryotes.
Proceedings of the National Academy of Sciences of the United States of America 20050921 40
The extent to which lateral genetic transfer has shaped microbial genomes has major implications for the emergence of community structures. We have performed a rigorous phylogenetic analysis of >220,000 proteins from genomes of 144 prokaryotes to determine the contribution of gene sharing to current prokaryotic diversity, and to identify "highways" of sharing between lineages. The inferred relationships suggest a pattern of inheritance that is largely vertical, but with notable exceptions among ...[more]
