Ontology highlight
ABSTRACT:
SUBMITTER: Moggs JG
PROVIDER: S-EPMC1247471 | biostudies-literature | 2004 Aug
REPOSITORIES: biostudies-literature
Moggs Jonathan G JG Ashby John J Tinwell Helen H Lim Fei Ling FL Moore David J DJ Kimber Ian I Orphanides George G
Environmental health perspectives 20040801 11
We used gene expression profiling to investigate whether the molecular effects induced by estrogens of different provenance are intrinsically similar. In this article we show that the physiologic estrogen 17-beta-estradiol, the phytoestrogen genistein, and the synthetic estrogen diethylstilbestrol alter the expression of the same 179 genes in the intact immature mouse uterus under conditions where each chemical has produced an equivalent gravimetric and histologic uterotrophic effect, using the ...[more]