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Fatal pulmonary infection associated with a novel organism, "para-streptomyces abscessus".

ABSTRACT: Actinomycetes are increasingly recognized as pathogenic in the immunocompromised host. We isolated an asporogenous, nonmotile, aerobic gram-positive rod from a transplant recipient with a fatal pulmonary infection. The pathology was similar to that associated with Rhodococcus equi, including intra-histiocytic localization. The organism was relatively inert in standard biochemical tests. 16S rRNA gene sequencing indicated a potentially unique organism most closely related to the genus Streptomyces, for which we propose the name "Para-streptomyces abscessus."

SUBMITTER: Nichols WG

PROVIDER: S-EPMC1248464 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature

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Fatal pulmonary infection associated with a novel organism, "para-streptomyces abscessus".

Nichols W Garrett WG Prentice Jennifer J Houze Yolanda Y Carlson LaDonna L Cookson Brad T BT

Journal of clinical microbiology 20051001 10

Actinomycetes are increasingly recognized as pathogenic in the immunocompromised host. We isolated an asporogenous, nonmotile, aerobic gram-positive rod from a transplant recipient with a fatal pulmonary infection. The pathology was similar to that associated with Rhodococcus equi, including intra-histiocytic localization. The organism was relatively inert in standard biochemical tests. 16S rRNA gene sequencing indicated a potentially unique organism most closely related to the genus Streptomyce ...[more]

PMID: 16208023

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