Macrolide resistance mediated by a Bifidobacterium breve membrane protein.
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ABSTRACT:
SUBMITTER: Margolles A
PROVIDER: S-EPMC1251533 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
Publications
Macrolide resistance mediated by a Bifidobacterium breve membrane protein.
Margolles Abelardo A Moreno José Antonio JA van Sinderen Douwe D de Los Reyes-Gavilán Clara G CG
Antimicrobial agents and chemotherapy 20051001 10
A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides. ...[more]
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