Ontology highlight
ABSTRACT:
SUBMITTER: Zanata SM
PROVIDER: S-EPMC125391 | biostudies-literature | 2002 Jul
REPOSITORIES: biostudies-literature
Zanata Silvio M SM Lopes Marilene H MH Mercadante Adriana F AF Hajj Glaucia N M GN Chiarini Luciana B LB Nomizo Regina R Freitas Adriana R O AR Cabral Ana L B AL Lee Kil S KS Juliano Maria A MA de Oliveira Elizabeth E Jachieri Saul G SG Burlingame Alma A Huang Lan L Linden Rafael R Brentani Ricardo R RR Martins Vilma R VR
The EMBO journal 20020701 13
Prions are composed of an isoform of a normal sialoglycoprotein called PrP(c), whose physiological role has been under investigation, with focus on the screening for ligands. Our group described a membrane 66 kDa PrP(c)-binding protein with the aid of antibodies against a peptide deduced by complementary hydropathy. Using these antibodies in western blots from two-dimensional protein gels followed by sequencing the specific spot, we have now identified the molecule as stress-inducible protein 1 ...[more]