Ontology highlight
ABSTRACT:
SUBMITTER: Klemke M
PROVIDER: S-EPMC125537 | biostudies-literature | 2001 Jul
REPOSITORIES: biostudies-literature
Klemke M M Kehlenbach R H RH Huttner W B WB
The EMBO journal 20010701 14
The >1 kb XL-exon of the rat XLalphas/Galphas gene encodes the 37 kDa XL-domain, the N-terminal half of the 78 kDa neuroendocrine-specific G-protein alpha-subunit XLalphas. Here, we describe a novel feature of the XL-exon, the presence of an alternative >1 kb open reading frame (ORF) that completely overlaps with the ORF encoding the XL-domain. The alternative ORF starts 32 nucleotides downstream of the start codon for the XL-domain and is terminated by a stop codon exactly at the end of the XL- ...[more]