Ontology highlight
ABSTRACT:
SUBMITTER: Kammerer M
PROVIDER: S-EPMC125586 | biostudies-literature | 2001 Sep
REPOSITORIES: biostudies-literature
The EMBO journal 20010901 17
The fly glial cell deficient/glial cell missing (glide/gcm) gene codes for a transcription factor that induces gliogenesis. Lack of its product eliminates lateral glial cells in the embryonic nervous system. Here we identify a second gene, glide2, that is homologous to glide/gcm in the binding domain and that is also necessary and sufficient to promote glial differentiation. glide2 codes for a transcription factor that displays a weaker and delayed expression compared with glide/gcm. The two gen ...[more]