Ontology highlight
ABSTRACT:
SUBMITTER: Bonnaud B
PROVIDER: S-EPMC1262775 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Bonnaud Bertrand B Beliaeff Jean J Bouton Olivier O Oriol Guy G Duret Laurent L Mallet François F
Retrovirology 20050922
<h4>Background</h4>The human HERV-W multicopy family includes a unique proviral locus, termed ERVWE1, whose full-length envelope ORF was preserved through evolution by the action of a selective pressure. The encoded Env protein (Syncytin) is involved in hominoid placental physiology.<h4>Results</h4>In order to infer the natural history of this domestication process, a comparative genomic analysis of the human 7q21.2 syntenic regions in eutherians was performed. In primates, this region was progr ...[more]