Ontology highlight
ABSTRACT:
SUBMITTER: Hirata D
PROVIDER: S-EPMC126291 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
Hirata Dai D Kishimoto Norihito N Suda Masako M Sogabe Yuki Y Nakagawa Sayuri S Yoshida Yasuko Y Sakai Keisuke K Mizunuma Masaki M Miyakawa Tokichi T Ishiguro Junpei J Toda Takashi T
The EMBO journal 20020901 18
Fission yeast cells identify growing regions at the opposite ends of the cell, producing the rod-like shape. The positioning of the growth zone(s) and the polarized growth require CLIP170-like protein Tip1 and the Ndr kinase Orb6, respectively. Here, we show that the mor2/cps12 mutation disrupts the localization of F-actin at the cell ends, producing spherical cells and concomitantly inducing a G(2) delay at 36 degrees C. Mor2 is important for the localization of F-actin at the cell end(s) but n ...[more]