Ontology highlight
ABSTRACT:
SUBMITTER: Lengeler KB
PROVIDER: S-EPMC126754 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Lengeler Klaus B KB Fox Deborah S DS Fraser James A JA Allen Andria A Forrester Keri K Dietrich Fred S FS Heitman Joseph J
Eukaryotic cell 20021001 5
The sexual development and virulence of the fungal pathogen Cryptococcus neoformans is controlled by a bipolar mating system determined by a single locus that exists in two alleles, alpha and a. The alpha and a mating-type alleles from two divergent varieties were cloned and sequenced. The C. neoformans mating-type locus is unique, spans >100 kb, and contains more than 20 genes. MAT-encoded products include homologs of regulators of sexual development in other fungi, pheromone and pheromone rece ...[more]