Ontology highlight
ABSTRACT:
SUBMITTER: Kantor R
PROVIDER: S-EPMC127108 | biostudies-literature | 2002 Apr
REPOSITORIES: biostudies-literature
Kantor Rami R Fessel W Jeffrey WJ Zolopa Andrew R AR Israelski Dennis D Shulman Nancy N Montoya Jose G JG Harbour Michael M Schapiro Jonathan M JM Shafer Robert W RW
Antimicrobial agents and chemotherapy 20020401 4
In order to track the evolution of primary protease inhibitor (PI) resistance mutations in human immunodeficiency virus type 1 (HIV-1) isolates, baseline and follow-up protease sequences were obtained from patients undergoing salvage PI therapy who presented initially with isolates containing a single primary PI resistance mutation. Among 78 patients meeting study selection criteria, baseline primary PI resistance mutations included L90M (42% of patients), V82A/F/T (27%), D30N (21%), G48V (6%), ...[more]