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RpoB mutation conferring rifampin resistance in Streptococcus pyogenes.

ABSTRACT: Streptococcus pyogenes BM4478 and Staphylococcus aureus BM4479 were isolated from a patient undergoing rifampin therapy. High-level resistance to rifampin was due to the following mutations in the rpoB gene: Ser522Leu in strain BM4478 and His526Asn and Ser574Leu in strain BM4479.

SUBMITTER: Aubry-Damon H 

PROVIDER: S-EPMC127170 | biostudies-literature | 2002 May

REPOSITORIES: biostudies-literature

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rpoB mutation conferring rifampin resistance in Streptococcus pyogenes.

Aubry-Damon Hélène H   Galimand Marc M   Gerbaud Guy G   Courvalin Patrice P  

Antimicrobial agents and chemotherapy 20020501 5

Streptococcus pyogenes BM4478 and Staphylococcus aureus BM4479 were isolated from a patient undergoing rifampin therapy. High-level resistance to rifampin was due to the following mutations in the rpoB gene: Ser522Leu in strain BM4478 and His526Asn and Ser574Leu in strain BM4479. ...[more]

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