Ontology highlight
ABSTRACT:
SUBMITTER: Meijer WJ
PROVIDER: S-EPMC1276709 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
The EMBO journal 20050929 20
Phage phi29 is a virulent phage of Bacillus subtilis with no known lysogenic cycle. Indeed, lysis occurs rapidly following infection of vegetative cells. Here, we show that phi29 possesses a powerful strategy that enables it to adapt its infection strategy to the physiological conditions of the infected host to optimize its survival and proliferation. Thus, the lytic cycle is suppressed when the infected cell has initiated the process of sporulation and the infecting phage genome is directed int ...[more]