Novel laminin-binding protein of Streptococcus pyogenes, Lbp, is involved in adhesion to epithelial cells.
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ABSTRACT:
SUBMITTER: Terao Y
PROVIDER: S-EPMC127702 | biostudies-literature | 2002 Feb
REPOSITORIES: biostudies-literature
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Novel laminin-binding protein of Streptococcus pyogenes, Lbp, is involved in adhesion to epithelial cells.
Terao Yutaka Y Kawabata Shigetada S Kunitomo Eiji E Nakagawa Ichiro I Hamada Shigeyuki S
Infection and immunity 20020201 2
The lbp gene, which encodes a laminin-binding protein (Lbp) of Streptococcus pyogenes, was found in all S. pyogenes M types. An Lbp-deficient mutant showed a significantly lower efficiency of adhesion to HEp-2 cells than did the wild-type strain. These results indicate that Lbp is one of the important S. pyogenes adhesins. ...[more]
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