Ontology highlight
ABSTRACT:
SUBMITTER: Secott TE
PROVIDER: S-EPMC127902 | biostudies-literature | 2002 May
REPOSITORIES: biostudies-literature
Secott T E TE Lin T L TL Wu C C CC
Infection and immunity 20020501 5
Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced attachment and ingestion of M. avium subsp. paratuberculosis by T-24 and Caco-2 cells. The results indicate that the interaction between FN and FAP-P facilitates attachment and inter ...[more]