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Multiplex PCR for simultaneous detection of macrolide and tetracycline resistance determinants in streptococci.

ABSTRACT: Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [erm(A), erm(B), and mef(A/E)] and tetracyclines [tet(M), tet(O), tet(K), and tet(L)] in streptococci.

SUBMITTER: Malhotra-Kumar S

PROVIDER: S-EPMC1280148 | biostudies-literature | 2005 Nov

REPOSITORIES: biostudies-literature

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Multiplex PCR for simultaneous detection of macrolide and tetracycline resistance determinants in streptococci.

Malhotra-Kumar Surbhi S Lammens Christine C Piessens Jasper J Goossens Herman H

Antimicrobial agents and chemotherapy 20051101 11

Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [erm(A), erm(B), and mef(A/E)] and tetracyclines [tet(M), tet(O), tet(K), and tet(L)] in streptococci. ...[more]

PMID: 16251336

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