Rhodopseudomonas palustris regulons detected by cross-species analysis of alphaproteobacterial genomes.

ABSTRACT: Rhodopseudomonas palustris, an alpha-proteobacterium, carries out three of the chemical reactions that support life on this planet: the conversion of sunlight to chemical-potential energy; the absorption of carbon dioxide, which it converts to cellular material; and the fixation of atmospheric nitrogen into ammonia. Insight into the transcription-regulatory network that coordinates these processes is fundamental to understanding the biology of this versatile bacterium. With this goal in mind, we predicted regulatory signals genomewide, using a two-step phylogenetic-footprinting and clustering process that we had developed previously. In the first step, 4,963 putative transcription factor binding sites, upstream of 2,044 genes and operons, were identified using cross-species Gibbs sampling.

SUBMITTER: Conlan S 

PROVIDER: S-EPMC1287613 | biostudies-literature | 2005 Nov

REPOSITORIES: biostudies-literature