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Inducible AmpC beta-lactamase of a new member Enterobacteriaceae.


ABSTRACT: Extensive biochemical testing and 16S rRNA and rpoB sequence analysis revealed that clinical strain CF01Ent1, initially identified as Buttiauxella agrestis by the use of Api 32 biochemical strips, is a new organism in the Enterobacteriaceae family. It produced an inducible AmpC-type beta-lactamase whose sequence shares 69 to 72% identity with those of the other AmpC-type beta-lactamases of ENTEROBACTERIACEAE: This enzyme exhibits an atypical high affinity for all beta-lactams tested.

SUBMITTER: Bonnet R 

PROVIDER: S-EPMC128800 | biostudies-literature | 2002 Oct

REPOSITORIES: biostudies-literature

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Inducible AmpC beta-lactamase of a new member Enterobacteriaceae.

Bonnet Richard R   Chanal Catherine C   Ageron Elisabeth E   Sirot Danielle D   De Champs Christophe C   Grimont Patrick P   Sirot Jacques J  

Antimicrobial agents and chemotherapy 20021001 10


Extensive biochemical testing and 16S rRNA and rpoB sequence analysis revealed that clinical strain CF01Ent1, initially identified as Buttiauxella agrestis by the use of Api 32 biochemical strips, is a new organism in the Enterobacteriaceae family. It produced an inducible AmpC-type beta-lactamase whose sequence shares 69 to 72% identity with those of the other AmpC-type beta-lactamases of ENTEROBACTERIACEAE: This enzyme exhibits an atypical high affinity for all beta-lactams tested. ...[more]

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