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CspA regulates pigment production in Staphylococcus aureus through a SigB-dependent mechanism.

ABSTRACT: We report that the cold shock protein CspA of Staphylococcus aureus is required for maximal production of pigment. Results from transcriptional studies revealed that loss of CspA resulted in decreased expression of genes needed for the biosynthesis of 4,4'-diaponeurosporene and the alternative sigma factor SigB.

SUBMITTER: Katzif S 

PROVIDER: S-EPMC1291268 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature

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CspA regulates pigment production in Staphylococcus aureus through a SigB-dependent mechanism.

Katzif Samuel S   Lee Eun-Hee EH   Law Anthony B AB   Tzeng Yih-Ling YL   Shafer William M WM  

Journal of bacteriology 20051201 23

We report that the cold shock protein CspA of Staphylococcus aureus is required for maximal production of pigment. Results from transcriptional studies revealed that loss of CspA resulted in decreased expression of genes needed for the biosynthesis of 4,4'-diaponeurosporene and the alternative sigma factor SigB. ...[more]