Ontology highlight
ABSTRACT:
SUBMITTER: Avivi A
PROVIDER: S-EPMC129335 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
Avivi Aaron A Oster Henrik H Joel Alma A Beiles Avigdor A Albrecht Urs U Nevo Eviatar E
Proceedings of the National Academy of Sciences of the United States of America 20020822 18
We demonstrated that a subterranean, visually blind mammal has a functional set of three Per genes that are important components of the circadian clockwork in mammals. The mole rat superspecies Spalax ehrenbergi is a blind subterranean animal that lives its entire life underground in darkness. It has degenerated eyes, but the retina and highly hypertrophic harderian gland are involved in photoperiodic perception. All three Per genes oscillate with a periodicity of 24 h in the suprachiasmatic nuc ...[more]