A retrocopy of a gene can functionally displace the source gene in evolution.
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ABSTRACT:
SUBMITTER: Krasnov AN
PROVIDER: S-EPMC1298928 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Publications
A retrocopy of a gene can functionally displace the source gene in evolution.
Krasnov Aleksey N AN Kurshakova Maria M MM Ramensky Vasily E VE Mardanov Pavel V PV Nabirochkina Elena N EN Georgieva Sofia G SG
Nucleic acids research 20051127 20
The e(y)2 gene of Drosophila melanogaster encodes the ubiquitous evolutionarily conserved co-activator of RNA polymerase II that is involved in transcription regulation of a high number of genes. The Drosophila e(y)2b gene, paralogue of the e(y)2 has been found. The analysis of structure of the e(y)2, e(y)2b and its orthologues from other species reveals that the e(y)2 gene derived as a result of retroposition of the e(y)2b during Drosophila evolution. The mRNA-derived retrogenes lack introns or ...[more]
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