Ontology highlight
ABSTRACT:
SUBMITTER: Drory O
PROVIDER: S-EPMC1299189 | biostudies-literature | 2004 Dec
REPOSITORIES: biostudies-literature
EMBO reports 20041201 12
Vacuolar H(+)-ATPase (V-ATPase) has a crucial role in the vacuolar system of eukaryotic cells. It provides most of the energy required for transport systems that utilize the proton-motive force that is generated by ATP hydrolysis. Some, but not all, of the V-ATPase subunits are homologous to those of F-ATPase and the nonhomologous subunits determine the unique features of V-ATPase. We determined the crystal structure of V-ATPase subunit C (Vma5p), which does not show any homology with F-ATPase s ...[more]