Ontology highlight
ABSTRACT:
SUBMITTER: Dittmar KA
PROVIDER: S-EPMC1299251 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Dittmar Kimberly A KA Sørensen Michael A MA Elf Johan J Ehrenberg Måns M Pan Tao T
EMBO reports 20050201 2
Aminoacylated (charged) transfer RNA isoacceptors read different messenger RNA codons for the same amino acid. The concentration of an isoacceptor and its charged fraction are principal determinants of the translation rate of its codons. A recent theoretical model predicts that amino-acid starvation results in 'selective charging' where the charging levels of some tRNA isoacceptors will be low and those of others will remain high. Here, we developed a microarray for the analysis of charged fract ...[more]