Ontology highlight
ABSTRACT:
SUBMITTER: Nicastro G
PROVIDER: S-EPMC1304461 | biostudies-literature | 2004 Aug
REPOSITORIES: biostudies-literature
Nicastro Giuseppe G Margiocco Paola P Cardinali Barbara B Stagnaro Paola P Cauglia Fabio F Cuniberti Carla C Collini Maddalena M Thomas David D Pastore Annalisa A Rocco Mattia M
Biophysical journal 20040801 2
The possibility of predicting the overall shape of a macromolecule in solution from its diffusional properties has gained increasing importance in the structural genomic era. Here we explore and quantify the influence that unstructured and flexible regions have on the motions of a globular protein, a situation that can occur from the presence of such regions in the natural sequence or from additional tags. I27, an immunoglobulin-like module from the muscle protein titin, whose structure and prop ...[more]