Survey of allelic expression using EST mining.
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ABSTRACT:
SUBMITTER: Ge B
PROVIDER: S-EPMC1310646 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
Publications
Survey of allelic expression using EST mining.
Ge Bing B Gurd Scott S Gaudin Tiffany T Dore Carole C Lepage Pierre P Harmsen Eef E Hudson Thomas J TJ Pastinen Tomi T
Genome research 20051101 11
Cis-acting allelic variation in gene regulation is a source of phenotypic variation. Consequently, recent studies have experimentally screened human genes in an attempt to initiate a catalog of genes possessing cis-acting variants. In this study, we use human EST data in dbEST as the source of allelic expression data, and the HapMap database to provide expected allele frequencies in human populations. We demonstrate a greater concordance of allele frequencies estimated from human ESTs in dbEST w ...[more]
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