Hemoglobin is expressed in alveolar epithelial type II cells.
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ABSTRACT:
SUBMITTER: Bhaskaran M
PROVIDER: S-EPMC1314978 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Publications
Hemoglobin is expressed in alveolar epithelial type II cells.
Bhaskaran Manoj M Chen Haifeng H Chen Zhongmong Z Liu Lin L
Biochemical and biophysical research communications 20050801 4
Hemoglobin is the main oxygen carrying heme protein in erythrocytes. In an effort to study the differential gene expression of alveolar epithelial type I and type II cells using DNA microarray technique, we found that the mRNAs of hemoglobin alpha- and beta-chains were expressed in type II cells, but not in type I cells. The microarray data were confirmed by RT-PCR. The mRNA expression of both chains decreased when type II cells trans-differentiated into type I-like cells. Immunocyto/histochemis ...[more]
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