Ontology highlight
ABSTRACT:
SUBMITTER: Kearns DB
PROVIDER: S-EPMC1315410 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Kearns Daniel B DB Losick Richard R
Genes & development 20051201 24
We have discovered that cells of Bacillus subtilis at the mid-exponential phase of growth are a mixed population of two strikingly different cell types. One type is single swimming cells (or cell doublets) in which the transcription factor for motility, sigma(D), is active (sigma(D) ON). The other type is long chains of sessile cells in which sigma(D) is inactive (sigma(D) OFF). The population is strongly biased toward sigma(D)-ON cells by the action of a novel regulatory protein called SwrA. Sw ...[more]