Ontology highlight
ABSTRACT:
SUBMITTER: Pegtel DM
PROVIDER: S-EPMC1316046 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Pegtel Dirk M DM Subramanian Aravind A Sheen Tzung-Shiahn TS Tsai Ching-Hwa CH Golub Todd R TR Thorley-Lawson David A DA
Journal of virology 20051201 24
Nonkeratinizing nasopharyngeal carcinomas (NPC) are >95% associated with the expression of the Epstein-Barr virus (EBV) LMP2A latent protein. However, the role of EBV, in particular, LMP2A, in tumor progression is not well understood. Using Affymetrix chips and a pattern-matching computational technique (neighborhood analysis), we show that the level of LMP2A expression in NPC biopsy samples correlates with that of a cellular protein, integrin-alpha-6 (ITGalpha6), that is associated with cellula ...[more]