Ontology highlight
ABSTRACT:
SUBMITTER: Nakano S
PROVIDER: S-EPMC1316115 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Nakano Shu-ichi S Uotani Yuuki Y Uenishi Kazuya K Fujii Masayuki M Sugimoto Naoki N
Nucleic acids research 20051215 22
On the basis of non-covalent bond interactions in nucleic acids, we synthesized the deoxyadenosine derivatives tethering a phenyl group (X) and a naphthyl group (Z) by an amide linker, which mimic a Watson-Crick base pair. Circular dichroism spectra indicated that the duplexes containing X and Z formed a similar conformation regardless of the opposite nucleotide species (A, G, C, T and an abasic site analogue F), which was not observed for the natural duplexes. The values among the natural duple ...[more]