Ontology highlight
ABSTRACT:
SUBMITTER: Shi K
PROVIDER: S-EPMC1317922 | biostudies-literature | 2005 Dec
REPOSITORIES: biostudies-literature
Shi Ke K Brown C Kent CK Gu Zu-Yi ZY Kozlowicz Briana K BK Dunny Gary M GM Ohlendorf Douglas H DH Earhart Cathleen A CA
Proceedings of the National Academy of Sciences of the United States of America 20051208 51
Many bacterial activities, including expression of virulence factors, horizontal genetic transfer, and production of antibiotics, are controlled by intercellular signaling using small molecules. To date, understanding of the molecular mechanisms of peptide-mediated cell-cell signaling has been limited by a dearth of published information about the molecular structures of the signaling components. Here, we present the molecular structure of PrgX, a DNA- and peptide-binding protein that regulates ...[more]