ABC transporters and azole susceptibility in laboratory strains of the wheat pathogen Mycosphaerella graminicola.
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ABSTRACT:
SUBMITTER: Zwiers LH
PROVIDER: S-EPMC132773 | biostudies-literature | 2002 Dec
REPOSITORIES: biostudies-literature
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ABC transporters and azole susceptibility in laboratory strains of the wheat pathogen Mycosphaerella graminicola.
Zwiers Lute-Harm LH Stergiopoulos Ioannis I Van Nistelrooy Johannes G M JG De Waard Maarten A MA
Antimicrobial agents and chemotherapy 20021201 12
Laboratory strains of Mycosphaerella graminicola with decreased susceptibilities to the azole antifungal agent cyproconazole showed a multidrug resistance phenotype by exhibiting cross-resistance to an unrelated chemical, cycloheximide or rhodamine 6G, or both. Decreased azole susceptibility was found to be associated with either decreased or increased levels of accumulation of cyproconazole. No specific relationship could be observed between azole susceptibility and the expression of ATP-bindin ...[more]
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