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Sakacin g, a new type of antilisterial bacteriocin.


ABSTRACT: Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2. Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity.

SUBMITTER: Simon L 

PROVIDER: S-EPMC134399 | biostudies-literature | 2002 Dec

REPOSITORIES: biostudies-literature

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Sakacin g, a new type of antilisterial bacteriocin.

Simon L L   Fremaux C C   Cenatiempo Y Y   Berjeaud J M JM  

Applied and environmental microbiology 20021201 12


Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2. Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity. ...[more]

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