Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence.
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ABSTRACT:
SUBMITTER: Park NY
PROVIDER: S-EPMC1346593 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
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Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence.
Park Na Young NY Lee Jeong Hyun JH Kim Myung Won MW Jeong Hee Gon HG Lee Byung Cheol BC Kim Tae Sung TS Choi Sang Ho SH
Infection and immunity 20060101 1
A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C(4) epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus. ...[more]
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