Ontology highlight
ABSTRACT:
SUBMITTER: Okamoto A
PROVIDER: S-EPMC1347018 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Okamoto Aki A Iwamoto Yasuhiko Y Maru Yoshiro Y
Molecular and cellular biology 20060201 3
Previous results of our cDNA microarray analysis to look for genes whose expression level correlates well with in vitro tubulogenesis by NP31 endothelial cells revealed the transcription factor ATF3 known to be responsive to stress such as reactive oxygen species (ROS). Anti-ATF3 small interfering RNA gave an inhibitory influence on tube formation by NP31 cells expressing an activated form of the vascular endothelial growth factor receptor 1 (VEGFR-1) kinase. When expression of ATF3 was regulate ...[more]