Mapping of Myxococcus xanthus social motility dsp mutations to the dif genes.
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ABSTRACT:
SUBMITTER: Lancero H
PROVIDER: S-EPMC134841 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Publications
Mapping of Myxococcus xanthus social motility dsp mutations to the dif genes.
Lancero Hope H Brofft Jennifer E JE Downard John J Birren Bruce W BW Nusbaum Chad C Naylor Jerome J Shi Wenyuan W Shimkets Lawrence J LJ
Journal of bacteriology 20020301 5
Myxococcus xanthus dsp and dif mutants have similar phenotypes in that they are deficient in social motility and fruiting body development. We compared the two loci by genetic mapping, complementation with a cosmid clone, DNA sequencing, and gene disruption and found that 16 of the 18 dsp alleles map to the dif genes. Another dsp allele contains a mutation in the sglK gene. About 36.6 kb around the dsp-dif locus was sequenced and annotated, and 50% of the genes are novel. ...[more]
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