Ontology highlight
ABSTRACT:
SUBMITTER: Platoshyn O
PROVIDER: S-EPMC1351366 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
Platoshyn Oleksandr O Remillard Carmelle V CV Fantozzi Ivana I Sison Tiffany T Yuan Jason X-J JX
Pflugers Archiv : European journal of physiology 20050729 2
Electrical excitability, which plays an important role in excitation-contraction coupling in the pulmonary vasculature, is regulated by transmembrane ion flux in pulmonary artery smooth muscle cells (PASMC). This study aimed to characterize the electrophysiological properties and molecular identities of voltage-gated Na(+) channels in cultured human PASMC. We recorded tetrodotoxin (TTX) sensitive and rapidly inactivating Na(+) currents with properties similar to those described in cardiac myocyt ...[more]