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The Bifidobacterium longum NCIMB 702259T ctr gene codes for a novel cholate transporter.

ABSTRACT: Preexposure of Bifidobacterium longum NCIMB 702259T to cholate caused increased resistance to cholate, chloramphenicol, and erythromycin. The B. longum ctr gene, encoding a cholate efflux transporter, was transformed into the efflux-negative mutant Escherichia coli KAM3, conferring resistance to bile salts and other antimicrobial compounds and causing the efflux of [14C]cholate.

SUBMITTER: Price CE

PROVIDER: S-EPMC1352250 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature

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The Bifidobacterium longum NCIMB 702259T ctr gene codes for a novel cholate transporter.

Price Claire E CE Reid Sharon J SJ Driessen Arnold J M AJ Abratt Valerie R VR

Applied and environmental microbiology 20060101 1

Preexposure of Bifidobacterium longum NCIMB 702259T to cholate caused increased resistance to cholate, chloramphenicol, and erythromycin. The B. longum ctr gene, encoding a cholate efflux transporter, was transformed into the efflux-negative mutant Escherichia coli KAM3, conferring resistance to bile salts and other antimicrobial compounds and causing the efflux of [14C]cholate. ...[more]

PMID: 16391136

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