Ontology highlight
ABSTRACT:
SUBMITTER: Worlock AJ
PROVIDER: S-EPMC135258 | biostudies-literature | 2002 Aug
REPOSITORIES: biostudies-literature
Worlock Ashley J AJ Smith Ronald L RL
Journal of bacteriology 20020801 16
A Zn2+ transport system encoded by the zntB locus of Salmonella enterica serovar Typhimurium has been identified. The protein encoded by this locus is homologous to the CorA family of Mg2+ transport proteins and is widely distributed among the eubacteria. Mutations at zntB confer an increased sensitivity to the cytotoxic effects of Zn2+ and Cd2+, a phenotype that suggests that the encoded protein mediates the efflux of both cations. A direct analysis of transport activity identified a capacity f ...[more]