Ontology highlight
ABSTRACT:
SUBMITTER: Aricescu AR
PROVIDER: S-EPMC135600 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Aricescu A Radu AR McKinnell Iain W IW Halfter Willi W Stoker Andrew W AW
Molecular and cellular biology 20020301 6
RPTPsigma is a cell adhesion molecule-like receptor protein tyrosine phosphatase involved in nervous system development. Its avian orthologue, known as cPTPsigma or CRYPalpha, promotes intraretinal axon growth and controls the morphology of growth cones. The molecular mechanisms underlying the functions of cPTPsigma are still to be determined, since neither its physiological ligand(s) nor its substrates have been described. Nevertheless, a major class of ligand(s) is present in the retinal basal ...[more]