Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes.
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ABSTRACT:
SUBMITTER: Niller HH
PROVIDER: S-EPMC136116 | biostudies-literature | 2002 Apr
REPOSITORIES: biostudies-literature
Publications
Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes.
Niller Hans Helmut HH Salamon Daniel D Uhlig Jörg J Ranf Stefanie S Granz Marcus M Schwarzmann Fritz F Wolf Hans H Minarovits Janos J
Journal of virology 20020401 8
Genomic footprints across Rp, Zp, and oriLyt of Epstein-Barr virus (EBV) have been conducted in a panel of latently infected B-cell lines. Close protein-base contacts were found about 360 nucleotides upstream of the Zp initiation site. Gel shifts and transient transfection assays indicated that an Sp1-NF1 locus may serve as a repressive transcriptional element against Zp induction from latent EBV genomes. ...[more]
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