Identification and expression of immunogenic proteins of a disease-associated marine turtle herpesvirus.
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ABSTRACT:
SUBMITTER: Coberley SS
PROVIDER: S-EPMC136575 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Publications
Identification and expression of immunogenic proteins of a disease-associated marine turtle herpesvirus.
Coberley Sadie S SS Condit Richard C RC Herbst Lawrence H LH Klein Paul A PA
Journal of virology 20021001 20
Herpesviruses are associated with several diseases of marine turtles, including lung-eye-trachea disease (LETD) and fibropapillomatosis. Two approaches were used to identify immunodominant antigens of LETV, the LETD-associated herpesvirus. The first approach targeted glycoprotein B, which is known to be immunogenic and neutralizing in other species. The second strategy identified LETV proteins recognized on Western blots by antibodies in immune green turtle plasma. A 38-kDa protein was resolved ...[more]
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