Ontology highlight
ABSTRACT:
SUBMITTER: Reid AH
PROVIDER: S-EPMC136643 | biostudies-literature | 2002 Nov
REPOSITORIES: biostudies-literature
Reid Ann H AH Fanning Thomas G TG Janczewski Thomas A TA McCall Sherman S Taubenberger Jeffery K JK
Journal of virology 20021101 21
The coding region of influenza A virus RNA segment 7 from the 1918 pandemic virus, consisting of the open reading frames of the two matrix genes M1 and M2, has been sequenced. While this segment is highly conserved among influenza virus strains, the 1918 sequence does not match any previously sequenced influenza virus strains. The 1918 sequence matches the consensus over the M1 RNA-binding domains and nuclear localization signal and the highly conserved transmembrane domain of M2. Amino acid cha ...[more]