Ontology highlight
ABSTRACT:
SUBMITTER: Malkova S
PROVIDER: S-EPMC1366689 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Biophysical journal 20050701 3
X-ray reflectivity is used to study the interaction of C2 domains of cytosolic phospholipase A(2) (cPLA(2)alpha-C2) with a Langmuir monolayer of 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine (SOPC) supported on a buffered aqueous solution containing Ca(2+). The reflectivity is analyzed in terms of the known crystallographic structure of cPLA(2)alpha-C2 domains and a slab model representing the lipid layer to yield an electron density profile of the lipid layer and bound C2 domains. This new me ...[more]