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Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide.


ABSTRACT: Staphylococcus aureus responds with protective strategies against phagocyte-derived reactive oxidants to infect humans. Herein, we report the transcriptome analysis of the cellular response of S. aureus to hydrogen peroxide-induced oxidative stress. The data indicate that the oxidative response includes the induction of genes involved in virulence, DNA repair, and notably, anaerobic metabolism.

SUBMITTER: Chang W 

PROVIDER: S-EPMC1367260 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature

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Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide.

Chang Wook W   Small David A DA   Toghrol Freshteh F   Bentley William E WE  

Journal of bacteriology 20060201 4


Staphylococcus aureus responds with protective strategies against phagocyte-derived reactive oxidants to infect humans. Herein, we report the transcriptome analysis of the cellular response of S. aureus to hydrogen peroxide-induced oxidative stress. The data indicate that the oxidative response includes the induction of genes involved in virulence, DNA repair, and notably, anaerobic metabolism. ...[more]

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