Ontology highlight
ABSTRACT:
SUBMITTER: Haugen P
PROVIDER: S-EPMC1370599 | biostudies-literature | 2004 Jul
REPOSITORIES: biostudies-literature
Haugen Peik P Runge Henry Joseph HJ Bhattacharya Debashish D
RNA (New York, N.Y.) 20040701 7
More than 1000 group I introns have been identified in fungal rDNA. Little is known, however, of the splicing and secondary structure evolution of these ribozymes. Here, we use a combination of comparative and biochemical methods to address the evolution and splicing of a vertically inherited group I intron found at position 788 in the fungal small subunit (S) rRNA. The ancestral state of the S788 intron contains a highly conserved core and an extended P5 domain typical of IC1 introns. In contra ...[more]