Ontology highlight
ABSTRACT:
SUBMITTER: Pan H
PROVIDER: S-EPMC1388092 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Pan Hui H Yan Bo-Shiun BS Rojas Mauricio M Shebzukhov Yuriy V YV Zhou Hongwei H Kobzik Lester L Higgins Darren E DE Daly Mark J MJ Bloom Barry R BR Kramnik Igor I
Nature 20050401 7034
An estimated eight million people are infected each year with the pathogen Mycobacterium tuberculosis, and more than two million die annually. Yet only about 10% of those infected develop tuberculosis. Genetic variation within host populations is known to be significant in humans and animals, but the nature of genetic control of host resistance to tuberculosis remains poorly understood. Previously we mapped a new genetic locus on mouse chromosome 1, designated sst1 (for supersusceptibility to tu ...[more]