Ontology highlight
ABSTRACT:
SUBMITTER: van den Ent F
PROVIDER: S-EPMC139093 | biostudies-literature | 2002 Dec
REPOSITORIES: biostudies-literature
van den Ent Fusinita F Møller-Jensen Jakob J Amos Linda A LA Gerdes Kenn K Löwe Jan J
The EMBO journal 20021201 24
It was the general belief that DNA partitioning in prokaryotes is independent of a cytoskeletal structure, which in eukaryotic cells is indispensable for DNA segregation. Recently, however, immunofluorescence microscopy revealed highly dynamic, filamentous structures along the longitudinal axis of Escherichia coli formed by ParM, a plasmid-encoded protein required for accurate segregation of low-copy-number plasmid R1. We show here that ParM polymerizes into double helical protofilaments with a ...[more]